ABSTRACT In view of a postulated role of the vigilance-promoting drug modafinil in depression, the interaction of…
ABSTRACT BACKGROUND: Benefit from selective serotonin reuptake inhibitor (SSRI) treatment in major depressive disorder (MDD) usually takes…
ABSTRACT INTRODUCTION: The extent to which modafinil and caffeine reverse fatigue effects (defined as performance decrements with…
ABSTRACT BACKGROUND: To investigate the effects of modafinil on regional cerebral blood flow (rCBF) in narcolepsy, we…
ABSTRACT Aodafinil is a unique wake-promoting agent for oral administration. Its pharmacological properties are distinct from those…
ABSTRACT We report a 59 year old woman with levodopa responsive Parkinson’s disease who developed excessive daytime…
ABSTRACT Narcolepsy-cataplexy is a neurological disorder associated with the inability to maintain wakefulness and abnormal intrusions of…
ABSTRACT Hypocretins/orexins are rapidly emerging as functionally important neurotransmitters. Two related neuropeptides (Hcrt-1/OXA, Hcrt-2/OXB) encoded by the…
ABSTRACT Narcolepsy-cataplexy, a disorder of excessive sleepiness and abnormalities of rapid eye movement (REM) sleep, results from…
ABSTRACT SUMMARY: In a multicenter, randomized, double-blind study the authors compared the efficacy of modafinil 400 mg…
