Tomas Thorne

Modafinil - Serotonin

Efficacy and Safety of Modafinil (Provigil((R))) for the Treatment of Fatigue in Multiple Sclerosis: A Two Centre Phase 2 Study

ABSTRACT Objective: To assess the efficacy and safety of modafinil for the treatment of fatigue in multiple…

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February 2, 2023

Modafinil for Drooling in Cerebral Palsy

ABSTRACT Two patients with spastic cerebral palsy recently treated with modafinil at the Walter Reed Army Medical…

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February 2, 2023
Modafinil Dopamine

Dopaminergic-Adrenergic Interactions in The Wake Promoting Mechanism of Modafinil

ABSTRACT Adrenergic signaling regulates the timing of sleep states and sleep state-dependent changes in muscle tone. Recent…

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February 20, 2023
Increased Dopaminergic Transmission

Increased Dopaminergic Transmission Mediates the Wake-Promoting Effects of CNS Stimulants

ABSTRACT Amphetamine-like stimulants are commonly used to treat sleepiness in narcolepsy. These compounds have little effect on…

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February 20, 2023
Modafinil - Dopamine

Modafinil Evokes Striatal [(3)H]Dopamine Release and Alters the Subjective Properties of Stimulants

ABSTRACT Modafinil is a mild psychostimulant used for the treatment of sleep and arousal-related disorders, and has…

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February 2, 2023
Modafinil - Cocaine

A Double-Blind, Placebo-Controlled Trial of Modafinil for Cocaine Dependence

ABSTRACT Despite years of active research, there are still no approved medications for the treatment of cocaine…

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February 2, 2023
Modafinil and Cocaine

Modafinil and Cocaine Interactions

ABSTRACT This Phase I trial evaluated the interaction between modafinil steady-state and cocaine. Twelve non-treatment seeking, cocaine…

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February 20, 2023
Modafinil Blood Pressure

Does Short-Term Treatment with Modafinil Affect Blood Pressure in Patients with Obstructive Sleep Apnea?

ABSTRACT OBJECTIVE: To investigate the effects of modafinil, a central nonamphetamine awakening substance, on blood pressure and…

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February 2, 2023
Modafinil Review

Stop the Boffins Before they Modafinil a Mule or Let Rats Enter the Olympics

The dangers and opportunities in sport for the appliance of science Harry Pearson I have never been…

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February 2, 2023
Clonidine and Modafinil

Modulation of the Acoustic Startle Response by the Level of Arousal: Comparison of Clonidine and Modafinil in Healthy Volunteers

ABSTRACT A sudden loud sound evokes an electromyographic (EMG) response from the orbicularis oculi muscle in humans…

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February 20, 2023