Drug May Help Night-Shift Workers
WASHINGTON, Aug. 5 (UPI) — Working at night and sleeping during the day is not natural for…
February 20, 2023
Tomas Thorne
Juicing the Brain
Research to limit mental fatigue among soldiers may foster controversial ways to enhance any person’s brain Physicians…
February 2, 2023
New Mechanism For Attentional Control In The Human Brain Discovered
A study by UC Davis researchers appearing in the journal Science on December 12, reports the discovery of a…
February 20, 2023
Fed OK Sought for ADHD Remedy ?
Attenace promising, Cephalon reports Cephalon Inc. has asked federal regulators to approve a version of its narcolepsy…
February 20, 2023
The Efficacy and Safety of Armodafinil as Treatment for Adults with Excessive Sleepiness Associated with Narcolepsy
ABSTRACT OBJECTIVE: This study assessed the efficacy and safety of armodafinil, the longer half-life enantiomer of modafinil,…
February 2, 2023
Systemic and Nasal Delivery of Orexin-A (Hypocretin-1) Reduces the Effects of Sleep Deprivation on Cognitive Performance in Nonhuman Primates
ABSTRACT Hypocretin-1 (orexin-A) was administered to sleep-deprived (30–36 h) rhesus monkeys immediately preceding testing on a multi-image…
February 2, 2023
FDA Warning Letter
Dear Mr. Kirsch: This letter objects to Cephalon Inc’s (Cephalon) dissemination of false or misleading promotional materials1Â for…
February 20, 2023
A Double-Blind, Placebo-Controlled Investigation of the Efficacy of Modafinil for Sustaining the Alertness and Performance of Aviators: a Helicopter Simulator Study
ABSTRACT RATIONALE: In 1998, the FDA approved modafinil for treating excessive daytime sleepiness in narcoleptics, and this…
February 20, 2023
Wake-Promoting and Sleep-Suppressing Actions of Hypocretin (Orexin): Basal Forebrain Sites of Action
ABSTRACT The hypocretins (orexins) are a newly identified peptide family comprised of two peptides, hypocretin-1 and hypocretin-2….
February 2, 2023
The Vigilance Promoting Drug Modafinil Increases Extracellular Glutamate Levels in the Medial Preoptic area and the Posterior Hypothalamus of the Conscious Rat: Prevention by Local GABAA Receptor Blockade
ABSTRACT The effects of modafinil on glutamatergic and GABAergic transmission in the rat medial preoptic area (MPA)…
February 20, 2023