New drug may help soldiers stay awake – Doctors unsure of long-term effect
U.S. soldiers are staying awake for days and nights on end in Iraq, and many are almost…
February 2, 2023
Basic
Sleep: A Functional Enigma
ABSTRACT Although continued total sleep deprivation is fatal, the function of sleep remains a mystery. Shorter durations…
February 19, 2023
It’s Wake-Up Time
Kiss your pillow good-bye. A new breed of drugs promises to do for drowsiness what Prozac did…
February 19, 2023
A Double-Blind, Placebo-Controlled, Ascending-Dose Evaluation of the Pharmacokinetics and Tolerability of Modafinil Tablets in Healthy Male Volunteers
ABSTRACT A randomized, double-blind, placebo-controlled, ascending-dose study was conducted to evaluate the pharmacokinetic and safety profiles of…
February 19, 2023
Narcolepsy. Signs, Symptoms, Differential Diagnosis, and Management
ABSTRACT Narcolepsy is a chronic neurologic disorder characterized by excessive daytime sleepiness and cataplexy and less often…
February 20, 2023
Modafinil-Associated Weight Loss in a Clozapine-Treated Schizoaffective Disorder Patient
ABSTRACT BACKGROUND: We report a case of weight loss associated with modafinil-initiation in a clozapine-treated man with…
February 20, 2023
Wake-Promoting Agents with Different Mechanisms of Action: Comparison of Effects of Modafinil and Amphetamine on Food Intake and Cardiovascular Activity
ABSTRACT Despite efforts to achieve a desirable weight, two-thirds of the population has an elevated body weight….
February 20, 2023
Etiologies and Sequelae of Excessive Daytime Sleepiness
ABSTRACT Excessive daytime sleepiness (EDS), the primary complaint of patients seen in sleep clinics, affects up to…
February 19, 2023
Modafinil Enhances the Increase of Extracellular Serotonin Levels Induced by the Antidepressant Drugs Fluoxetine and Imipramine: A dual Probe Microdialysis Study in Awake Rat
ABSTRACT In view of a postulated role of the vigilance-promoting drug modafinil in depression, the interaction of…
February 19, 2023